Human Food Safety Senior Scientist
Zoetis

Zoetis Veterinary Medicine Research and Development (VMRD) seeks an enthusiastic colleague for a challenging and fast-paced position in research and development of veterinary medicines in Kalamazoo, Michigan. As an integral member of research and development project teams, the candidate will design and implement studies to understand the absorption, distribution, metabolism, and elimination of veterinary pharmaceuticals in food producing animals with a goal of demonstrating the safety of food products intended for human consumption. The candidate will collaborate extensively with bioanalytical, target animal safety, toxicology, pharmacokinetics, environmental, clinical, and regulatory scientists as part of a multidisciplinary team.

Responsibilities include:

• Developing and validating robust analytical methods to quantify residues of veterinary pharmaceuticals and biotherapeutics in blood/plasma, tissues, excreta, and other matrices at the low ng/g to pg/g level.

• Developing study designs and protocols for in vitro and in vivo studies.

• Collaborating with other VMRD groups and partners to provide high quality and seamless support for projects.

• Serving as Study Director, Principal Investigator, or Contributing Scientist in GLP studies.

• Monitoring studies conducted at Contract Research Organizations.

• Writing or contributing to study reports and regulatory submissions.

• Rapid response to regulatory, manufacturing, and product support queries globally.

• Participate/lead continuous improvement and innovation efforts within the Metabolism & Safety residue group.

• Occasional domestic or international travel: usually ~5% depending on the nature and stage of project(s).

• Opportunity to participate in industry working groups in the future.

Minimum skills, education, & attributes:

• BS, MS, or PhD in chemistry, biochemistry, biology, pharmaceuticals, or a related field.

• PhD (post-graduate experience preferred) or BS/MS with at least 5 years of experience in the veterinary or human pharmaceutical, or agricultural/food industry.

• Experience developing de novo analytical methods for new chemical entities in biomatrices by UHPLC-MS/MS, HPLC-UV/FL, radiometric, and other methods.

• Experience in sample collection and preparation methodologies for biomatrices.

• Demonstrated skills in scientific writing (e.g., protocols, reports, journal articles).

• Excellent written and oral communication abilities (verbal and written English).

• Ability to work in a collaborative and dynamic team environment in a global company.

Desirable skills, education, & attributes:

• Analysis of biotherapeutics (monoclonal antibodies, endogenous or recombinant proteins) in biological matrices.

• Working in a regulated environment (e.g., GLP).

• Working with radioisotopes (14C, 3H).

• Metabolite profiling and/or structure elucidation of metabolites by NMR, mass spectrometry, etc.

• In vitro metabolism or in vivo ADME studies.

• Working with E-notebooks, LIMS, laboratory automation and liquid handling systems.

• Familiar with regulatory requirements (e.g., VICH/ICH, FDA/CVM, OECD) for human or veterinary pharmaceuticals.

Full time

Regular

Colleague

Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.